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Indication: VELCADE® (bortezomib) for Injection is indicated for the treatment of patients with mantle cell lymphoma who have received at least one prior therapy. VELCADE is contraindicated in patients with hypersensitivity to bortezomib, boron, or mannitol. VELCADE should be administered under the supervision of a physician experienced in the use of antineoplastic therapy.
For further information about VELCADE and Mantle Cell Lymphoma (MCL), select a menu item in the table below.
Menu Item Topic
Mechanism VELCADE: mechanism of action
Disease Background Background on MCL
PINNACLE Trial Design and Results PINNACLE phase 2 trial overview
Safety Profile MCL specific and integrated analysis of safety
Dosing Schedule Dosing for MCL
Dose Modification Guidlines Dosing recommendations for managing side effects
Handling and Administration Handling and administration guidelines
Important Safety Information Contraindications, warnings, and precautions
Reimbursement Reimbursement assistance program
Additional Information Downloadable files and phone number for VELCADE and MCL information
References Journal articles and other cited sources


For full Prescribing Information click here. (pdf) (74KB)
For further information about VELCADE® (bortezomib) for Injection, call 1-866-VELCADE (U.S. clinicians only).
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