PUBLICATIONS 1998
Adams J. Behnke M. Chen S. Cruickshank A. A. Dick L. R. Grenier L. Klunder J. M. Ma Y. T. Plamondon L. Stein R. L. 1998 Potent and selective inhibitors of the proteasome: Dipeptyidyl boronic acids. Bioorganic & Medicinal Chemistry Letters. 8:333-338
Banerjee P. Kleyn P. W. Knowles J. A. Lewis C. A. Ross B. M. Parano E. Kovats S. G. Lee J. J. Penchaszadeh G. K. Ott J. Jacobson S. G. Gilliam T. C. 1998 TULP1 mutation in two extended Dominican kindreds with autosomal recessive retinitis pigmentosa. Nature Genetics. 18:177-179
Banerjee P. Lewis C. A. Kleyn P. W. Shugart Y. Y. Ross B. M. Penchaszadeh G. K. Ott J. Jacobson S. G. Gilliam T. C. Knowles J. A. 1998 Homozygosity and physical mapping of the autosomal recessive retinitis pigmentosa locus (RP14) on chromosome 6p21.3. Genomics. 48:171-177
Behn P. S. Wasson J. Chayen S. Smolovitch I. Thomas J. Glaser B. 1998 Hepatocyte nuclear factor 1-alpha coding mutations are an uncommon contributor to early-onset type 2 diabetes in Ashkenazi Jews. Diabetes. 47:967-969
Blackburn C. Guan B. Fleming P. Shiosaki K. Tsai S. 1998 Parallel synthesis of 3-aminoimidazo [1,2-a] pyridines and pyrazines by a new three-component condensation. Tetrahedron Letters. 39:3635-3638
Blackburn C. 1998 A three-component solid-phase synthesis of 3-aminoimdazo[1,2-A]azines. Tetrahedron Letters. 39:5469-5472
Cai X. Scannell R. T. Yaeger D. Hussoin M. S. Killian D. B. Qian C. Eckman J. Yeh C. G. Ip S. Shen T. Y. 1998 (±) -Trans-2-[3-methoxy-4- (4-chlorophenylthioethoxy) -5-(N-methyl -N- hydroxyureidyl) methylphenyl] -5 -(3,4,5- trimethoxyphenyl) tetrahydrofuran (CMI-392), a potent dual 5-lipoxygenase inhibitor and platelet-activating factor receptor antagonist. Journal of Medicinal Chemistry. 41:1970-1979
Chen Y. Hancock W. W. Marks R. Gonnella P. Weiner H. L. 1998 Mechanisms of recovery from experimental allergic encephalomyelitis: T cell deletion and immune deviation in myelin basic protein T cell receptor transgenic mice. Journal of Neuroimmunology. 82:149-159
Cloninger C. R. Kaufmann C. A. Faraone S. V. Malaspina D. Svrakic D. M. Harkavyfriedman J. Surez B. K. Matise T. C. Shore D. Lee H. Hampe C. L. Wynne D. Drain C. Markel P. D. Zambuto C. T. Schmitt K. Tsuang M. T. 1998 Genome-wide search for schizophrenia susceptibility loci: The NIMH Genetics Initiative and Millennium Consortium. American Journal of Medical Genetics. 81:275-281
Dinulescu D.M. Fan W. Boston B.A. McCall M. L. Lamoreux, K.J. Moore K.J. Montagno J. Cone R.D. 1998 Mahogany (mg) stimulates feeding and increases basal metabolic rate independent of its suppression of agouti. Proceedings of the National Academy of Sciences of the United States of America. 95:12707-12712
Dragic T. Trkola A. Lin S. W. Nagashima K. A. Kajumo F. Zhao L. Olson W. C. Wu L. Mackay C. R. Allaway G. P. Sakmar T. P. Moore J. P. Maddon P. J. 1998 Amino-terminal substitutions in the CCR5 coreceptor impair gp120 binding and human immunodeficiency virus type 1 entry. Journal of Virology. 72:279-285
Duncan L. M. Deeds J. Hunter J. Shao J. Holmgren L. M. Woolf E. A. Tepper R. I. Shyjan A. W. 1998 Down-regulation of the novel gene melastatin correlates with potential for melanoma metastasis. Cancer Research. 58:1515-1520
Elsner J. Kluthe C. Petering H. Kimmig D. Smolarski R. Ponath P. Kapp A. 1998 Eotaxin-2 activates chemotaxis-related events and release of reactive oxygen species via pertussis toxin sensitive G-proteins in human eosinophils. European Journal of Immunology. 28:2152-2158
Faraibe S. V. Matise T. Svrakic D. Papple J. Malaspina D. Suarez B. Hampe C. Zambuto C. T. Schmitt K. Meyer J. Markel P. Lee H. Harkavy-Friedman J. Kaufmann C. Cloninger C. R. Tsuang M. T. 1998 Genome scan of European-American schizophrenia pedigrees: Results of the NIMH Genetics Initiative and Millennium Consortium. American Journal of Medical Genetics. 81:290-295
Faria T. N. LaRosa G. J. Wilen E. Liao J. Gudas L. J. 1998 Characterization of genes which exhibit reduced expression during the retinoic acid-induced differentiation of F9 teratocarcinoma cells: involvement of cyclin D3 in RA-mediated growth arrest. Molecular and Cellular Endocrinology. 143:155-166
Farzan M. Choe H. Vaca L. Martin K. Sun Y. Desjardins E. Ruffing N. Wu L. Wyatt R. Gerard N. Gerard C. Sodroski J. 1998 A tyrosine-rich region in the N-terminus of CCR5 is important for human immunodeficiency virus type 1 entry and mediates an association between gp120 and CCR5. Journal of Virology. 72:1160-1164
Ganju R. K. Brubaker S. A. Meyer J. Dutt P. Yang Y. Qin S. Newman W. Groopman J. E. 1998 The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways. Journal of Biological Chemistry. 273:23169-23175
Ganju R. K. Dutt P. Wu L. Newman W. Avraha H. Avraham S. Groopman J. E. 1998 Beta-chemokine receptor CCR5 signals via the novel tyrosine kinase RAFTK. Blood. 91:791-797
Ghorpade A. Xia M. Q. Hyman B. T. Persidsky Y. Nukuna A. Bock P. Che M. Limoges J. Gendelman H. E. Makcay C. R. 1998 Role of the beta-chemokine receptors CCR3 and CCR5 in human immunodeficiency virus type 1 infection of monocytes and microglia. Journal of Virology. 72:3351-3361
Gonzalo J.A. Lloyd C.M. Wen D.Y. Albar J.P. Wells T.N.C. Proudfoot A. Martinez C. Dorf M. Bjerke T. Coyle A.J. Gutierrezramos J.C. 1998 The coordinated action of CC chemokines in the lung orchestrates allergic inflammation and airway hyperresponsiveness. Journal of Experimental Medicine. 188:157-167
Grey S. Csizmadia V. Hancock W. W. 1998 Differential effect of tumor necrosis factor-alpha on thrombomodulin gene expression by human monocytes versus endothelial cells. International Journal of Hematology. 67:53-62
Hancock W. W. 1998 Endothelial cell blind panel: Immunocytochemical analysis report. Leucocyte Typing VI. 734-738
Hancock W. W Buelow R. Sayegh M. H. Turka L. A. 1998 Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes. Nature Medicine. 4:1392-1396
Healy A. M. Hancock W. W. Christie P. D. Rayburn H. B. Rosenberg R. D. 1998 Intravascular coagulation activation in a murine model of thrombomodulin deficiency: Effects of lesion size, age and hypoxia on fibrin deposition. Blood. 92:4188-4197
Hsieh F. Keshishian H. Muir C. 1998 Automated high throughput multiple target screening of molecular libraries by microfluidic MALDI-TOF MS. Journal of Biomolecular Screening. 3:189-198
Hunter J. J. Shao J. Smutko J. S. Dussault B. J. Nagle D. L. Woolf E. A. Holmgren L. M. Moore K. J. Shyjan A.W. 1998 Chromosomal localization and genomic characterization of the mouse melastatin gene (Mlsn1). Genomics. 54:116-123
Jacobson M. 1998 Anti-apoptosis therapy: A new way of treating neural degeneration? [Review]. Current Biology. 18:R418-R421
Jin T. Amzel M. Devreotes P. N. Wu L. 1998 Selection of G-beta subunits with point mutations that fail to activate specific signaling pathways in vivo: Dissecting cellular responses mediated by a heterotrimeric G protein in Dictyostelium discoideum. Molecular Biology of the Cell. 9:2949-2961
Kalidas K. Wasson J. Glaser B. Meyer J. M. Duprat L. J. White M. F. Permutt M. A. 1998 Mapping of the human insulin receptor substrate-2 gene, identification of a linked polymorphic marker and linkage analysis in families with type II diabetes - no evidence for a major susceptibility role. Diabetologia. 41:1389-1391
Kaufmann C. A. Sureez B. Malaspina D. Pepple J. Svrakic D. Markel P. D. Meyer J. Zambuto C. T. Schmitt K. Matise T. C. Friedman J. M. H. Hampe C. Lee H. Shore D. Wynne D. Faraone S. V. Tsuang M. T. Cloniger C. R. 1998 NIMH Genetics Initiative Millennium Schizophrenia Consortium: Linkage analysis of African-American pedigrees. American Journal of Medical Genetics. 81:282-289
Kitayama J. Mackay C. R. Ponath P. D. Springer T. A. 1998 The C-C chemokine receptor CCR3 participates in stimulation of eosinophil arrest on inflammatory endothelium in shear flow. Journal of Clinical Investigation. 101:2017-2024
Kleyn P.W. Vesell E.S. 1998 Genetic variation as a guide to drug development. Science. 281:1820-1821
Kohno Y. Shimojo N. Aoyagi M. Sannomiya Y. Nishimuta T. Kojima H. Katsuki T. Tomiita M. Lazarovits A. I. Ringler D. Niimi H. 1998 Increased expression of alpha 4 beta 7 integrin on food allergen-stimulated CD4+ T cells in active food allergic enterocolitis. Allergology International. 47:99-102
Lee F. S. Peters R. T. Dang L. C. Maniatis T. 1998 MEKK1 activates both I-kappa B kinase alpha and I-kappa B kinase beta. Proceedings of the National Academy of Sciences of the United States of America. 95:9319-9324
Lloyd C. Gutierrez-Ramos J.C. 1998 The role of chemokines in tissue inflammation and autoimmunity in renal diseases. Current Opinion in Nephrology and Hypertension. 7:281-287
Lohning M. Stroehmann A. Coyle A. J. Grogan J. L. Lin S. Gutierrez-Ramos J. C. Levinson D. Radbruch A. Lamradt T. 1998 T1/ST2 is preferentially expressed on murine TH2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for TH2 effector function. Proceedings of the National Academy of Sciences of the United States of America. 95:6930-6935
McCormack T. A. Cruikshank A. A. Greneir L. Melandri F. D. Nunes S. L. Plamondon L. Stein R. L. Dick L. R. 1998 Kinetic studies of the branched chain amino acid preferring peptidase activity of the 20S proteasome: Development of a continuous assay and inhibition by tripeptide aldehydes and clasto-lactacystin beta-lactone. Biochemistry. 37:7792-7800
Newman W. Mirabelli C. K. 1998 The link between inflammatory disease and patterns of leukocyte recruitment. Expert Opinion in Investigational Drugs. 7:19-15
Palombella V. J. Conner E. M. Fuseler J. W. Destree A. Davis J. M. Laroux F. S. Wolf R. E. Huang J. Brand S. Elliott P. J. Lazarus D. McCormack T. Parent L. Stein R. Adams J. Grisham M. B. 1998 Role of the proteasome and NF-kappa-B in streptococcal cell wall-induced polyarthritis. Proceedings of the National Academy of Sciences of the United States of America. 95:15671-15676
Pease J. E. Wang J. Ponath P. D. Murphy P. M. 1998 The N-terminal extracellular segments of the chemokine receptors CCR1 and CCR3 are determinants for MIP-1 alpha and eotaxin binding respectively, but a second domain is essential for efficient receptor activation. Journal of Biological Chemistry. 273:19972-19976
Peled A. Gonzalo J. A. Lloyd C. Gutierrez-Ramos J. C. 1998 The chemotactic cytokine eotaxin acts as a granulocyte-macrophage colony-stimulating factor during lung inflammation. Blood. 91:1909-1916
Piali L. Weber C. LaRosa G. Mackay C. Springer T. A. Clark-Lewis I. Moser B. 1998 The chemokine receptor CXCR3 mediates rapid and shear-resistant adhesion-induction of effector T lymphocytes by the chemokines IP10 and Mig. European Journal of Immunology. 28:961-972
Qin S. Rottman J. B. Myers P. Kassam N. Weinblatt M. Loeetscher M. Koch A. E. Moser B. Mackay C. R. 1998 The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. Journal of Clinical Investigation. 101:746-754
Ruffing N. Sullivan N. Sharmeen L. Sodroski J. Wu L. 1998 CCR5 has an expanded ligand-binding repertoire and is the primary receptor used by MCP-2 on activated T cells. Cellular Immunology. 189:160-168
Sallusto F. Lenig D. MacKay C. R. Lanzavecchia A. 1998 Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. Journal of Experimental Medicine. 187:875-883
Sallusto F. Schaerli P. Loetscher P. Schaniel C. Lening D. MacKay C. R. 1998 Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation. European Journal of Immunology. 28:2760-2769
Sanz M. J. Ponath P. D. Mackay C. R. Newman W. Masayuki M. Tamatani T. Flanagan B. F. Lobb R. R. Williams T. J. Nourshargh S. Jose P. J. 1998 Human eotaxin induces alpha-4 and beta-2 integrin-dependent eosinophil accumulation in rat skin in vivo: Delayed generation of eotaxin in response to IL-4. Journal of Immunology. 160:3569-3576
Shoji M. Hancock W. W. Abe K. Micko C. Casper K. A. Baine R. M. Wilcox J. N. Danave I. Dillehay D. L. Matthews E. Contrino J. Morrissey J. H. Gordon S. Edgington T. S. Kudryk B. Kreutzer D. L. Rickles F. R. 1998 Activation of coagulation and angiogenesis in cancer: immunohistochemical localization in situ of clotting proteins and vascular endothelial growth factor in human cancer. American Journal of Pathology. 152:399-411
Shroff H. N. Schwender C. F. Baxter A. D. Brookfield F. Payne L. J. Cochran N. A. Gallant D. L. Briksin M. J. 1998 Novel modified tripeptide inhibitors of alpha-4 beta-7 mediated lymphoid cell adhesion to MAdCAM-1. Bioorganic & Medicinal Chemistry Letters. 8:1601-1606
Tan K. Casasnovas J. M. Liu J. Briskin M. F. Springer T. A. Wang J. H. 1998 The structure of immunoglobulin superfamily domains 1 and 2 of MAdCAM-2 reveals novel features important for integrin recognition. Structure. 6:793-801
Topper J.N. DiChiara M.R. Brown J.D. Williams A.J. Falb D. Collins T. Gimbrone M.A. Jr. 1998 CREB binding protein is required coactivator for Smad-dependent transforming growth factor beta transcriptional responses in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 95:9506-9511
Topper J. N. Cai J. X. Stavrakis G. Anderson K. R. Woolf E. A. Sampson B. A. Schoen F. J. Falb D. Gimbrone M. A. 1998 Human prostaglandin transporter gene (hPGT) is regulated by fluid mechanical stimuli in cultured endothelial cells and expressed in vascular endothelium in vivo. Circulation. 98:2396-2403
Varban M. L. Rinninger F. Wang N. Fairchild-Huntress V. Dunmore J. H. Fang Q. Gosselin M. L. Dixon K. L. Deeds J. D. Acton S. L. Tall A. R. Huszar D. 1998 Targeted mutation reveals a central role for SR-BI in hepatic selective uptake of high density lipoprotein cholesterol. Proceedings of the National Academy of Sciences of the United States of America. 95:4619-4624
