PUBLICATIONS 1997
Blackburn C. Albericio F. Kates S. A. 1997 Functionalized resins and linkers for solid-phase synthesis of small molecules. Drugs of the Future. 22:1007-1025
Bleul C. C. Wu L. Hoxie J. A. Springer T. A. Mackay C. R. 1997 The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lympocytes. Proceedings of the National Academy of Sciences of the United States of America. 94:1925-1930
Briskin M. Winsor-Hines D. Shyjan A. Bloom S. Wilson J. McEvoy L. M. Butcher E. C. Kassam N. Mackay C. R. Newman W. Ringler D. J. 1997 Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue. American Journal of Pathology. 151:97-110
Busfield S. J. Michnick D. A. Chickering T. W. Revett T. L. Ma J. Woolf E. A. Comrack C. A. Dussault B. J. Woolf J. Goodearl A. D. Gearing D. P. 1997 Characterization of a neuregulin-related gene, Don-1, that is highly expressed in restricted regions of the cerebellum and hippocampus. Molecular & Cellular Biology. 17:4007-4014
Carson K. G. Schwender C. F. Shroff H. N. Cochran N. A. Gallant D. L. Briskin M. J. 1997 Sulfonopeptide inhibitors of leukocyte adhesion. Bioorganic & Medicinal Chemistry Letters. 7:711-714
Conner E. M. Brand S. Davis J. M. Laroux F. S. Palombella V. J. Fuseler J. W. Kang D. Y. Wolf R. E. Grisham M. B. 1997 Proteasome inhibiton attenuates nitric oxide synthase expression, VCAM-1 transcription and the development of chronic colitis. Journal of Pharmacology and Experimental Therapeutics. 282:1615-1622
Devos R. Guisez Y. Vanderheyden J. White D. W. Kalai M. Fountoulakis M. Plaetinck G. 1997 Ligand-independent dimerization of the extracellular domain of the leptin receptor and determination of the stoichiometry of leptin binding. Journal of Biological Chemistry. 272:18304-18310
Dick L. R. Cruikshank A. A. Destree A. T. Grenier L. McCormack T. A. Melandri F. D. Nunes S. L. Palombella V. J. Parent L. A. Plamondon L. Stein R. L. 1997 Mechanistic studies on the inactivation of the proteasome by lactacystin in cultured cells. Journal of Biological Chemistry. 272:182-188
Dogan A. Du M. Koulis A. Briskin M. J. Isaacson P. G. 1997 Expression of lymphocyte homing receptors and vascular addressins in low-grade gastric B-cell lymphomas of mucosa-associated lymphoid tissue. American Journal of Pathology. 151:1361-1369
Evans D. M. Herman L. W. 1997 Identification of peptide ligands specific for the sugar-binding site of concanavalin A by screening a synthetic peptide combinatorial library. Journal of Biomolecular Screening. 2:225-233
Farzan M. Choe H. Martin K. A. Sun Y. Sidelko M. Mackay C. R. Gerard N. P. Sodroski J. Gerard C. 1997 HIV-1 entry and macrophage inflammatory protein-1beta-mediated signaling are independent functions of the chemokine receptor CCR5. Journal of Biological Chemistry. 272:6854-6857
Gerber B. O. Zanni M. P. Uggucioni M. Loetscher M. Mackay D. R. Pichler W. J. Yawalkar N. Baggiolini M. Moser B. 1997 Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils. Current Biology. 7:836-843
Gimeno R. E. Dembski M. Weng X. Deng N. Shyjan A. W. Gimeno C. J. Iris F. Ellis S. J. Woolf E. A. Tartaglia L. A. 1997 Cloning and characterization of an uncoupling protein homolog: A potential molecular mediator of human thermogenesis. Diabetes. 46:900-906
Glucksmann M. A. Lehto M. Tayber O. Scotti S. Berkemeier L. Pulido J. C. Wu Y. Nir W. J. Fang L. Markel P. Munnelly K. D. Goranson J. Orho M. Young B. M. Whitacre J. L. McMenimen C. Wantman M. Tuomi T. Warram J. Forsblom C. M. Carlsson M. Rosenzweig J. 1997 Novel mutations and a mutational hotspot in the MODY3 gene. Diabetes. 46:1081-1086
Gutierrez-Ramos J. C. Bluethmann H. 1997 Molecules and mechanisms operating in septic shock: Lessons from knockout mice [Review]. Immunology Today. 18:329-34
Harriman G. C. B. 1997 Synthesis of small and medium sized 2,2-disubstituted lactams via the "intramolecular" three component Ugi reaction. Tetrahedron Letters 38:5591-5594
Hayashi H. Abdollah S. Qiu Y. Cai J. Xu Y. Y. Grinnell B. W. Richardson M. A. Topper J. N. Gimbrone M. A. Jr. Wrana J. L. Falb D. 1997 The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling. Cell. 89:1165-1173
He J. Chen Y. Farzan M. Choe H. Ohagen A. Gartner S. Busciglio J. Yang X. Hofmann W. Newman W. Mackay C. R. Sodroski J. Gabuzda D. 1997 CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia. Nature. 385:645-649
Heath H. Qin S. Rao P. Wu L. LaRosa G. Kassam N. Ponath P. D. Mackay C. R. 1997 Chemokine receptor usage by human eosinophils: The importance of CCR3 demonstrated using an antagonistic monoclonal antibody. Journal of Clinical Investigation. 99:178-184
Higgins P. J, Ko J. L. Lobell R. Sardonini C. Alessi M. K. Yeh C. G. 1997 A soluble chimeric complement inhibitory protein that possesses both decay-accelerating and factor I cofactor activities. Journal of Immunology. 158: 2872-2881
Huszar D. Lynch C. A. Fairchild-Huntress V. Dunmore J. H. Fang Q. Berkemeier L. R. Gu W. Kesterson R. A. Boston B. A. Cone R. D. Smith F. J. Campfield L. A. Burn P. Lee F. 1997 Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell. 88:131-141
Jiang W. Gerhold D. Kmiec E. B. Hauser M. Becker J. M. Koltin Y. 1997 The topoisomerase I gene from Candida albicans. Microbiology. 143:377-386
Karim M. A. Nagle D. L. Kandil H. H. Burger J. Moore K. J. Spritz R. A. 1997 Mutations in the Chediak-Higashi syndrome gene (CHS1) indicate requirement for the complete 3801 amino acid CHS protein. Human Molecular Genetics. 6:1087-1089
Kim A. C. Peters L. L. Knoll J. H. M. Van Huffel C. Ciciotte S. L. Kleyn P. W. Chishti A. H. 1997 Limatin (LIMAB1), an actin-binding lim protein, maps to mouse chromosome 19 and human chromosome 10q25, a region frequently deleted in human cancers. Genomics. 46:291-293
Lee F. S. Hagler J. Chen Z. Maniatis T. 1997 Activation of the I-kappa B-alpha kinase complex by MEKK1, a kinase of the JNK pathway. Cell. 88:213-222
Lillie J. 1997 Probing the genome for new drugs and targets with DNA arrays [Review]. Drug Development Research. 41:160-172
Lloyd C. M. Gonzalo J. A. Salant D. J. Just J. Gutierrez-Ramos J. C. 1997 Intercellular adhesion molecule-1 deficiency prolongs survival and protects against the development of pulmonary inflammation during murine lupus. Journal of Clinical Investigation. 100:963-971
Lloyd C. M. Minto A. W. Dorf M. E. Proudfoot A. Wells T. N. Salant D. J. Gutierrez-Ramos J. C. 1997 RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis. Journal of Experimental Medicine. 185:1371-1380
Lloyd C. M. Dorf M. E. Proudfoot A. Salant D. J. Gutierrez-Ramos J. C. 1997 Role of MCP-1 and RANTES in inflammation and progression to fibrosis during murine crescentic nephritis. Journal of Leukocyte Biology. 62:676-680
Mackay C. R. 1997 Chemokines: What chemokine is that? Current Biology. 7: R384-R386
Palecanda A. Briskin M. J. Issekutz T. B. 1997 Rat mast cell lines bind to the vascular cell adhesion molecule-1 (VCAM-1) and the mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Journal of Immunology. 158:2904-2910
Picarella D. Hurlbut P. Rottman J. Shi X. Butcher E. Ringler D. J. 1997 Monoclonal antibodies specific for beta-7 integrin and MAdCAM-1 reduce inflammation in the colon of scid mice reconstituted with CD45RBhi CD4+ T cells. Journal of Immunology. 158:2099-2106
Reilly P. R. Boshar M. F. Holtzman S. H. 1997 Ethical issues in genetic research: Disclosure and informed consent. Nature Genetics. 15:16-20
Sallusto F. Mackay C. Lanzavecchia A. 1997 Selective expression of the eotaxin receptor CCR3 by human type 2 T lymphocytes suggests a mechanism for sustaining esonophilic inflammatory reaction. Science. 277:2005-2007
Samson M. LaRosa G. Libert F. Detheux M. Paindavoine P. Vassart G. Parmentier M. 1997 The second extracellular loop of CCR5 is the major determinant of ligand specificity. Journal of Biological Chemistry. 272:24934-24941
Stellato C. Collins P. Ponath P. D. Soler D. Newman W. LaRosa G. Li H. White J. Schwiebert L. M. Bickel C. Liu M. Bochner B. S. Williams T. Schleimer R. P. 1997 Production of the novel C-C chemokine MCP-4 by airway cells and comparison of its biological activity to other C-C chemokines. Journal of Clinical Investigation. 99:926-936
Tidswell M. Pachynski R. Wu S. Qiu S. Q. Dunham E. Briskin M. F. Cochran N. Kilshaw P. J. Lazarovits A. I. Andrew D. P. Butcher E. C. Yednock T. A. Erle D. J. 1997 Structure/function analysis of the integrin beta-7 subunit: Identification of domains involved in adhesion to MAdCAM-1. Journal of Immunology. 159:1497-1505
Topper J. N. Wasserman S. M. Anderson K. R. Cai J. Falb D. Gimbrone M. A. Jr. 1997 Expression of the bumetanide-sensitive Na-K-Cl cotransporter BSC2 is differentially regulated by fluid mechanical and inflammatory cytokine stimuli in vascular endothelium. Journal of Clinical Investigation. 99:2941-2949
Topper J. N. Cai J. Qiu Y. Anderson K. R. Xu Y. Y. Deeds J. D. Feeley R. Gimeno C. J. Woolf E. A. Tayber O. Mays G. G. Sampson B. A. Schoen F. J. Gimbrone M. A. Jr. Falb D. 1997 Vascular MADs: Two novel MAD-related genes selectively inducible by flow in human vascular endothelium. Proceedings of the National Academy of Sciences of the United States of America. 94:9314-9319
Uguccioni M. Mackay C. R. Ochensberger B. Loetscher P. Rhis S. LaRosa G. Ponath P. Rao P. Baggiolinie M. Dahinden C. 1997 High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4 and other chemokines. Journal of Clinical Investigation. 100:1137-1143
Ying S. Robinson D. S. Meng Q. Rottman J. Kennedy R. Ringler D. J. Mackay C. R. Daugherty B. L. Springer M. S. Durham S. R. Williams T. J. Kay A. B. 1997 Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma. Association with airway hyperresponsiveness and predominant co-localization of eotaxin mRNA to bronchial epithelial and endothelial cells. European Journal of Immunology. 27:3507-3516
