PUBLICATIONS 2000
An W. F. Bowlby M. R. Bett M. Cao J. Ling H. P. Mendoza G. Hinson J. W. Mattsson K. I. Strassle B. W. Trimmer J. S. Rhodes K. J. 2000 Modulation of A-type potassium channels by a family of calcium sensors. Nature. 403:553-556
Auerbach W. Dunmore J. H. Fairchild-Huntress V. Fang Q. Auerbach A. B. Huszar D. Joyner A. L. 2000 Establishment and chimera analysis of 129/svEv- and C57BL/6-derived mouse embryonic stem cell lines. BioTechniques. 29:1024
Bertin J. Guo Y. Wang L. Srinivasula S. M. Jacobson M. D. Poyet J. L. Merriam S. Du M. Q. Dyer M. J. S. Robison K. E. DiStefano P. S. Alnermi E. S. 2000 CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B. Journal of Biological Chemistry. 275:41082-41086
Blackburn C. Guan B. 2000 A novel dealkylation affording 3-aminoimidazo[1,2-a]pyridines: Access to new substitution patterns by solid-phase synthesis. Tetrahedron Letters. 41:1495-1500
Bray G. A. Tartaglia L. A. 2000 Medicinal strategies in the treatment of obesity. Nature. 404:672-677
Busfield S. J. Comrack C. A. Yu G. Chickering T. W. Smutko J. S. Zhou H. Leiby K. R. Holmgren L. M. Gearing D. P. Pan Y. 2000 Identification and gene organization of three novel members of the IL-1 family on human chromosome 2. Genomics. 66:213-216
Coyle A. J. Lehar S. Lloyd C. Tian J. Delaney T. Manning S. Nguyen T. Burwell T. Schneider H. Gonzalo J.A. Gosselin M. Owen L.R. Rudd C.E. Guiterrez-Ramos J. C. 2000 The CD28-related molecule ICOS is required for effective T cell-dependent immune responses. Immunity. 13:95-105
Coyle A. J. Lloyd C. M. Guiterrez-Ramos J. C. 2000 Biotherapeutic targets for the treatment of allergic airway disease. American Journal of Respiratory & Critical Care Medicine. 162:S170-S184
Deeds J. Cronin F. Duncan L. M. 2000 Patterns of melastatin mRNA expression in melanocytic tumors. Human Pathology. 31:1346-1356
Donoghue M. Hsieh F. Baronas E. Godbout K. Gosselin M. Stagliano N. Donovan M. Woolf B. Robison K. Jeyaseelan R. Breitbart R. E. Acton S. 2000 A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circulation Research. 87:E1-E9
Donovan MJ, Lin MI, Wiegn P, Ringstedt T, Kraemer R, Hahn R, Wang S, Ibanez CF, Rafii S, Hempstead BL. 2000 Brain derived neurotrophic factor is an endothelial cell survival factor required for intramyocardial vessel stabilization. Development. 127(21):4531-40.
Fawcett P. Eichenberger P. Losick R. Youngman P. 2000 The transcriptional profile of early to middle sporulation in Bacillus subtilis. Proceedings of the National Academy of Sciences of the United States of America. 97:8063-8068
Frankel A. Man S. Elliott P. Adams J. Kerbel R. S. 2000 Lack of Multicellular Drug Resistance Observed in Human Ovarian and Prostate Carcinoma Treated with the Proteasome Inhibitor PS-341. Clinical Cancer Research. 6:3719-3728
Galvin K. M. Donovan M. J. Lynch C. A. Meyer R. I. Paul R. J. Lorenz J. N. Fairchild-Huntress V. Dixon K. L. Dunmore J. H. Gimbrone M. A. Falb D. Huszar D. 2000 A role for Smad6 in development and homeostasis of the cardiovascular system. Nature Genetics. 24:171-174
Gao W. Topham P. S. King J. A. Smiley S. T. Csizmadia V. Lu. B. Gerard C. J. Hancock W. W. 2000 Targeting of the chemokine receptor CCR1 suppresses development of acute and chronic cardiac allograft rejection. Journal of Clinical Investigation. 105:35-44
Gonzalo J. A. Lloyd C. M. Peled A. Delaney T. Coyle A. J. Gutierrez-Ramos J. G. 2000 Critical involvement of the chemotactic axis CXCR4/stromal cell-derived factor-1 alpha in the inflammatory component of allergic airway disease. Journal of Immunology. 165:499-508
Gutierrez-Ramos J. C. Lloyd C. Kapsenberg M. L. Gonzalo J. A. Coyle A. J. 2000 Non-redundant functional groups of chemokines operate in a coordinate manner during the inflammatory response in the lung. Immunological Reviews. 177:31-42
Hancock W. W. Lu B. Gao W. Csizmadia B. Faia K. King J. A. Smiley S. T. Ling M. Gerard N. P. Gerard C. 2000 Requirement of the chemokine receptor CXCR3 for acute allograft rejection. Journal of Experimental Medicine. 192:1515-1519
Harriman G. C. B. Shao J. X. Luly J. R. 2000 Synthesis of 4-substituted 4-arylpiperdines. Tetrahedron Letters. 41:8853-8856
Huszar D. Varban M. L. Rinninger F. Feeley R. Arai T. Fairchild-Huntress V. Donovan M. J. Tall A. R. 2000 Increased LDL cholesterol and atherosclerosis in LDL receptor-deficient mice with attenuated expression of scavenger receptor B1. Arteriosclerosis Thrombosis & Vascular Biology. 20:1068-1073
Jandrot-Perrus M. Busfield S. Lagrue A. H. Xiong X. M. Debili N. Chickering T. Le Couedic J.P. Goodearl A. Dussault B. Fraser C. Vainchenker W. Villeval J. L. 2000 Cloning, characterization, and functional studies of human and mouse glyhcoporotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily. Blood. 96:1798-1807
Lambrecht B.N. De Veerman M. Coyle A. J. Guiterrez-Ramos J.C. Thielemans K. Pauwels R. A. 2000 Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation. Journal of Clinical Investigation. 106:551-559
Lightcap E. S. McCormack T. A. Pien C. S. Chau V. Adams J. Elliott P. J. 2000 Proteasome inhibition measurements: clinical application. Clinical Chemistry. 46:673-683
Lloyd C. M. Delaney T. Nguyen T. Tian J. Martinez C. Coyle A. J. Gutierrez-Ramos J. C. 2000 CC chemokine receptor (CCR)3/eotaxin is followed by CCR4/monocyte-derived chemokine in mediating pulmonary T helper lymphocyte type 2 recruitment after serial antigen challenge in vivo. Journal of Experimental Medicine. 191:265-273
McCarthy J. J. Hilfiker R. 2000 The use of single-nucleotide polymorphism maps in pharmacogenomics. Nature Biotechnology. 18:505-508
Read M. A. Brownell J. E. Gladysheva T. B. Hottelet M. Parent L. A. Coggins M. B. Pierce J. W. Podust V. N. Luo R. S. Chau V. Palombella V. J. 2000 Nedd8 modification of Cul-1 activates SCF beta(TrCp)-dependent ubiquitination of I kappa B alpha. Molecular & Cellular Biology. 20:2326-2333
Rottman J. B. Slavin A. J. Silva R. Weiner H. L. Gerard C. G. Hancock W. W. 2000 Leukocyte recruitment during onset of experimental allergic encephalomyelitis is CCR1 dependent. European Journal of Immunology. 30:2372-2377
Sander C. 2000 Genomic medicine and the future of health care. Science. 287:1977-1978
Sica A. Saccani A. Bottazzi B. Bernasconi S. Allavena P. Gaetano B. Fei P. LaRosa G. Scotton C. Balkwill F. Mantovani A. 2000 Defective expression of the monocyte chemotactic protein-1 receptor CCR2 in macrophages associated with human ovarian carcinoma source. Journal of Immunology. 164:733-738
Smiley S.T. Csizmadia V. Gao W. Turka L.A. Hancock W.W. 2000 Differential effects of cyclosporin A, methylprednisolone, mycophenolate, and rapamycin on CD154 induction and requirement for NF kappa B - Implications for tolerance induction. Transplantation. 70:415-419
Williams C. 2000 Biotechnology match making: Screening orphan ligands and receptors. Current Opinion in Biotechnology. 11:42-46
Williams C. Addona T. A. 2000 The integration of SPR biosensors with mass spectrometry: Possible applications for proteome analysis. Trends in Biotechnology. 18:45-48
