PUBLICATIONS 2003
Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, Chen H. 2003 Chronic Inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. Journal of Clinical Investigation 112(12):1821-30.
Gaussin V, Tomlinson JE, Depre C, Engelhardt S, Antos CL, Takagi G, Hein L, Topper JN, Liggett SB, Olson EN, Lohse MJ, Vatner SF, Vatner DE. 2003 Common genomic response in different mouse models of beta-adrenergic-induced cardiomyopathy. Circulation. 108(23):2926-33
Tomlinson JE, Topper JN. 2003 New insights into endothelial diversity. Current Atherosclerosis Reports. 5(3):223-9.
Yang RB, Ng CK, Wasserman SM, Komuves LG, Gerritsen ME, Topper JN. 2003 A novel interleukin-17 receptor-like protein identified in human umbilical vein endothelial cells antagonizes basic fibroblast growth factor-induced signaling. Journal of Biological Chemistry. 278(35):33232-8.
Lippert E, Yowe DL, Gonzalo JA, Justice JP, Webster JM, Fedyk ER, Hodge M, Miller C, Gutierrez-Ramos JC, Borrego F, Keane-Myers A, Druey KM. 2003. Role of regulator of G protein signaling 16 in inflammation-induced T lymphocyte migration and activation. The Journal of Immunology. 171(3):1542-55.
Richardson P.G. Barlogie B. Berenson J. Singhal S. Jagannath S. Irwin D. Rajkumar S.V. Srkalovic G. Alsina M. Alexanian R. Siegel D. Orlowski R.Z. Kuter D. Limentani S.A. Lee S. Hideshima T. Esseltine D.L. Kauffman M. Adams J. Schenkein D.P. Anderson K.C. 2003 A phase 2 study of bortezomib in relapsed, refractory myeloma. New England Journal of Medicine. 348(26):2609-17.
Varilo T, Paunio T, Parker A, Perola M, Meyer J, Terwilliger JD, Peltonen L. 2003
The interval of linkage disequilibrium (LD) detected with microsatellite and SNP markers in chromosomes of Finnish populations with different histories. Human Molecular Genetics. 12(1):51-9.
Ross JS, Ginsburg GS. 2003 The Integration of Molecular Diagnostics with Therapeutics. American Journal of Clinical Pathology 119(1):26-36.
Ross JS, Gray K, Gray GS, Worland PJ, Rolfe M. 2003 Anticancer antibodies. American Journal of Clinical Pathology. 119(4):472-85.
Roubenoff R. 2003 Catabolism of Aging: is it an inflammatory process?
Current Opinions in Clinical Nutrition and Metabolic Care 6(3):295-9.
Castro AC, Dang LC, Soucy F, Grenier L, Mazdiyasni H, Hottelet M, Parent L, Pien C, Palombella V, Adams J. 2003 Novel IKK Inhibitors: B-Carbolines.
Bioorganic and Medicinal Chemistry Letters 13(14):2419-22.
Grant EP, Coyle AJ, Gutierrez-Ramos JC 2003 Informatics and the immune system: the expanding IL-1 and B7 protein families. Seminars in Immunology. 15(4):225-31.
Sanchez-Fueyo A, Tian J, Picarella D, Domenig C, Zheng XX, Sabatos CA, Manlongat N, Bender O, Kamradt T, Kuchroo VK, Gutierrez-Ramos JC, Coyle AJ, Strom TB. 2003 Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance. Nature Immunology 4(11):1093-101.
McCarthy JJ, Meyer J, Moliterno DJ, Newby LK, Rogers WJ, Topol EJ; GenQuest multicenter study. 2003 Evidence for substantial effect modification by gender in a large-scale genetic association study of metabolic syndrome among coronary heart disease patients. Human Genetics 114(1):87-98.
McCarthy JJ, Lewitzky S, Reeves C, Permutt A, Glaser B, Groop LC, Lehner T, Meyer JM. 2003 Polymorphisms of the HDL receptor gene associated with HDL cholesterol levels in diabetic kindred from three populations. Human Heredity. 55(4):163-70.
McCarthy JJ, Lehner T, Reeves C, Moliterno DJ, Newby LK, Rogers WJ, Topol EJ; Genequest investigators. 2003 Association of genetic variants in the HDL receptor, SR-B1, with abnormal lipids in women with coronary artery disease. Journal of Molecular Genetics. 40(6):453-8.
Ross JS, Linette GP, Stec J, Ross MS, Anwar S, Boguniewicz A. 2003 DNA ploidy and cell cycle analysis in breast cancer. American Journal of Clinical Pathology. 120 Suppl:S72-84.
Carlson JA, Slominski A, Linette GP, Mysliborski J, Hill J, Mihm MC Jr, Ross JS. 2003 Malignant melanoma 2003: predisposition, diagnosis, prognosis, and staging. American Journal of Clinical Pathology.120 Suppl:S101-27.
Ross JS, Fletcher JA, Bloom KJ, Linette GP, Stec J, Clark E, Ayers M, Symmans WF, Pusztai L, Hortobagyi GN. 2003 HER-2/neu testing in breast cancer. American Journal of Clinical Pathology.120 Suppl:S53-71.
Bembenek ME, Jain S, Prack A, Li P, Chee L, Cao W, Spurling H, Roy R, Fish S, Rokas M, Parsons T, Meyers R. 2003 Development of a high-throughput assay for two inositol-specific phospholipase Cs using a scintillation proximity format. Assay and Drug Development Technologies. 1(3):435-43.
Ficenec D, Osborne M, Pradines J, Richards D, Felciano R, Cho RJ, Chen RO, Liefeld T, Owen J, Ruttenberg A, Reich C, Horvath J, Clark T. 2003 Computational knowledge integration in biopharmaceutical research. Briefings in Bioinformatics. 4(3):260-78.
Darwin KH, Ehrt S, Gutierrez-Ramos JC, Weich N, Nathan CF. 2003 The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide. Science. 302(5652):1963-6.
Schmidt-Supprian M, Courtois G, Tian J, Coyle AJ, Israel A, Rajewsky K, Pasparakis M. 2003 Mature T cells depend on signaling through the IKK complex. Immunity. 19(3):377-89.
Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, Golenbock DT, Coyle AJ, Liao SM, Maniatis T. 2003 IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nature Immunology 4(5):491-6.
Sabatos CA, Chakravarti S, Cha E, Schubart A, Sanchez-Fueyo A, Zheng XX, Coyle AJ, Strom TB, Freeman GJ, Kuchroo VK. 2003 Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance. Nature Immunology. 4(11):1102-10.
Bakewell SJ, Nestor P, Prasad S, Tomasson MH, Dowland N, Mehrotra M, Scarborough R, Kanter J, Abe K, Phillips D, Weilbaecher KN. 2003 Platelet and osteoclast beta3 integrins are critical for bone metastasis. Proceedings of the National Academy of Sciences. 100(24):14205-10.
Donoghue M, Wakimoto H, Maguire CT, Acton S, Hales P, Stagliano N, Fairchild-Huntress V, Xu J, Lorenz JN, Kadambi V, Berul CI, Breitbart RE. 2003 Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins. Journal of Molecular and Cellular Cardiology. 35(9):1043-53.
Girardin SE, Boneca IG, Carneiro LA, Antignac A, Jehanno M, Viala J, Tedin K, Taha MK, Labigne A, Zahringer U, Coyle AJ, DiStefano PS, Bertin J, Sansonetti PJ, Philpott DJ. 2003 Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan. Science. 300(5625):1584-7.
Williams JA. 2003 Hedgehog signaling pathway as a target for therapeutic intervention in basal cell carcinoma. Drug News and Perspectives. 16(10):657-62.
Gretler DD. 2003 Pharmacokinetic and pharmacodynamic properties of eptifabatide in healthy subjects receiving unfractionated heparin or the low-molecular-weight heparin enoxaparin. Clinical Therapeutics.25(10):2564-74.
Andre P, LaRocca T, Delaney SM, Lin PH, Vincent D, Sinha U, Conley PB, Phillips DR. 2003 Anticoagulants (thrombin inhibitors) and aspirin synergize with P2Y12 receptor antagonism in thrombosis. Circulation. 108(21):2697-703.
Prasad KS, Andre P, He M, Bao M, Manganello J, Phillips DR. 2003 Soluble CD40 ligand induces beta3 integrin tyrosine phosphorylation and triggers platelet activation by outside-in signaling. Proceedings of the National Academy of Sciences. 100(21):12367-71.
Gerritsen ME, Tomlinson JE, Zlot C, Ziman M, Hwang S. 2003 Using gene expression profiling to identify the molecular basis of the synergistic actions of hepatocyte growth factor and vascular endothelial growth factor in human endothelial cells. British Journal of Pharmacology. 140(4):595-610.
Prasad KS, Andre P, Yan Y, Phillips DR. 2003 The platelet CD40L/GP IIb-IIIa axis in atherothrombotic disease. Current Opinions in Hematology. 10(5):356-61.
Conley PB, Delaney SM. 2003 Scientific and therapeutic insights into the role of the platelet P2Y12 receptor in thrombosis. Current Opinions in Hematology. 10(5):333-8.
Andre P, Delaney SM, LaRocca T, Vincent D, DeGuzman F, Jurek M, Koller B, Phillips DR, Conley PB. 2003 P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries. Journal of Clinical Investigation. 112(3):398-406.
Xu H, Dembski M, Yang Q, Yang D, Moriarty A, Tayber O, Chen H, Kapeller R, Tartaglia LA. 2003 Dual specificity mitogen-activated protein (MAP) kinase phosphatase-4 plays a potential role in insulin resistance. Journal of Biological Chemistry. 278(32):30187-92.
Adams J. 2003 The proteasome: structure, function, and role in the cell. Cancer Treatment Reviews. 29 Suppl 1:3-9.
Chen Y, Miller C, Mosher R, Zhao X, Deeds J, Morrissey M, Bryant B, Yang D, Meyer R, Cronin F, Gostout BS, Smith-McCune K, Schlegel R. 2003 Identification of cervical cancer markers by cDNA and tissue microarrays. Cancer Research. 63(8):1927-35.
Wu L, Pan J, Thoroddsen V, Wysong DR, Blackman RK, Bulawa CE, Gould AE, Ocain TD, Dick LR, Errada P, Dorr PK, Parkinson T, Wood T, Kornitzer D, Weissman Z, Willis IM, McGovern K. 2003 Novel small-molecule inhibitors of RNA polymerase III. Eukaryotic Cell. 2(2):256-64.
Adams J. 2003 Potential for proteasome inhibition in the treatment of cancer. Drug Discovery Today. 8(7):307-15.
Nannizzi-Alaimo L, Alves VL, Phillips DR. 2003 Inhibitory effects of glycoprotein IIb/IIIa antagonists and aspirin on the release of soluble CD40 ligand during platelet stimulation. Circulation. 107(8):1123-8.
Ross J, Gray K, Schenkein D, Greene B, Gray GS, Shulok J, Worland PJ, Celniker A, Rolfe M. 2003 Antibody-based therapeutics in oncology. Expert Review of Anticancer Therapy. 3(1):107-21.
